| 产品特性：生物试剂 | 是否进口：否 | 级别：其它 |
| 含量：99％ | 品牌：上海生物网 | 用途范围：科研 |
| 产品名称：生物试剂 | 是否危险化学品：否 |
技术规格
| Background: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different ***forms, have been reported for this gene. |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | BAX |
| Immunogen: | Fusion protein of human BAX |
| Full name: | BCL2 associated X, apoptosis regulator |
| Synonyms: | BCL2L4 |
| SwissProt: | Q07812 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human liver cancer and Human gastric cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 21 kDa |
| WB Positive control: | LOVO, RAW264.7, A549 cell lysates |
| WB Recommended dilution: | 1000-5000 |
