| 产品特性：生物试剂 | 是否进口：否 | 级别：其它 |
| 含量：99％ | 品牌：上海生物网 | 用途范围：科研 |
| 产品名称：生物试剂 | 是否危险化学品：否 |
技术规格
| Background: | The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer&＃39;s disease. |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | CASP3 |
| Immunogen: | Fusion protein of human CASP3 |
| Full name: | caspase 3 |
| Synonyms: | CPP32; SCA-1; CPP32B |
| SwissProt: | P42574 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human esophagus cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 32 kDa |
| WB Positive control: | K562 cell lysate |
| WB Recommended dilution: | 500-2000 |
